LY9 Protein (AA 48-454) (His-Avi Tag)
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- Antigène Voir toutes LY9 (CD229) Protéines
- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 48-454
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette LY9 protéine est marqué à la His-Avi Tag.
- Fonction
- Human CD229/SLAMF3 Protein
- Séquence
- Lys48-Lys454
- Attributs du produit
- Recombinant Human CD229/SLAMF3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Lys48-Lys454.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
- Autre désignation
- CD229 (CD229 Produits)
- Synonymes
- LY9 Protein, CD229 Protein, SLAMF3 Protein, hly9 Protein, mLY9 Protein, AI893573 Protein, Lgp100 Protein, Ly-9 Protein, T100 Protein, lymphocyte antigen 9 Protein, LY9 Protein, Ly9 Protein
- Sujet
- CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells.
- Poids moléculaire
- 47.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- Pathways
- BCR Signaling
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