MFAP5 Protein (AA 22-173) (Fc Tag)

N° du produit ABIN7275231

Détail du produit

Antigène: MFAP5 (Microfibrillar Associated Protein 5 (MFAP5))

Type de proteíne: Recombinant

Attributs du protein: AA 22-173

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MFAP5 protéine est marqué à la Fc Tag.

Fonction: Human MFAP5 Protein

Séquence: Ile22-Leu173

Attributs du produit: Recombinant Human MFAP5 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile22-Leu173.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS ( pH 7.4).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: MFAP5 (Microfibrillar Associated Protein 5 (MFAP5))

Autre désignation: MFAP5 (MFAP5 Produits)

Synonymes: MFAP5 Protein, MAGP2 Protein, MP25 Protein, MAGP-2 Protein, microfibrillar associated protein 5 Protein, microfibril associated protein 5 Protein, MFAP5 Protein, Mfap5 Protein

Sujet: Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC.

Poids moléculaire: 44.1 kDa. Due to furin cleavage and glycosylation, the protein migrates to 32-38 kDa and 55-65 kDa based on Tris-Bis PAGE result.