Macrophage Scavenger Receptor 1 Protein (MSR1) (AA 77-451) (His tag)

N° du produit ABIN7275296

Détail du produit

Antigène: Macrophage Scavenger Receptor 1 (MSR1)

Type de proteíne: Recombinant

Attributs du protein: AA 77-451

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Macrophage Scavenger Receptor 1 protéine est marqué à la His tag.

Fonction: Human MSR1 Protein

Séquence: Lys77-Leu451

Attributs du produit: Recombinant Human MSR1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Lys77-Leu451.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Macrophage Scavenger Receptor 1 (MSR1)

Autre désignation: MSR1 (MSR1 Produits)

Synonymes: CD204 Protein, SCARA1 Protein, SR-A Protein, SRA Protein, phSR1 Protein, phSR2 Protein, MRS-A Protein, MSR Protein, MSR-A Protein, SR-AI Protein, SR-AII Protein, Scara1 Protein, Scvr Protein, MSR1 Protein, RGD1564316 Protein, macrophage scavenger receptor 1 Protein, scavenger receptor class A member 5 Protein, MSR1 Protein, Msr1 Protein, SCARA5 Protein

Sujet: The macrophage scavenger receptor 1 (Msr1, also called SRA) is a pattern recognition receptor primarily expressed on myeloid cells, which plays an important role in the maintenance of immune homeostasis. Msr1 promotes the pathogenesis of virus-induced FH by enhancing induction of neutrophil NETosis and subsequent complement activation. Targeting Msr1 may be employed as a new immunotherapeutic strategy for FH.

Poids moléculaire: 42.39 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result.