NCR1 Protein (AA 22-255) (His tag)

N° du produit ABIN7275355

Détail du produit

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Type de proteíne: Recombinant

Attributs du protein: AA 22-255

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette NCR1 protéine est marqué à la His tag.

Fonction: Mouse NKp46/NCR1/CD335 Protein

Séquence: Glu22-Asn255

Attributs du produit: Recombinant Mouse NKp46/NCR1/CD335 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu22-Asn255.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Autre désignation: NKp46 (NCR1 Produits)

Synonymes: CD335 Protein, LY94 Protein, NK-p46 Protein, NKP46 Protein, Ly94 Protein, NKp46 Protein, KILR-1 Protein, Nk-p46 Protein, Nkp46 Protein, natural cytotoxicity triggering receptor 1 Protein, NCR1 Protein, Ncr1 Protein

Sujet: NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.

Poids moléculaire: 27.7 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.

UniProt: Q8C567

Pathways: Regulation of Leukocyte Mediated Immunity