PGLYRP1 Protein (AA 22-196) (Fc Tag)

N° du produit ABIN7275449

Détail du produit

Antigène: PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))

Type de proteíne: Recombinant

Attributs du protein: AA 22-196

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PGLYRP1 protéine est marqué à la Fc Tag.

Fonction: Human PGLYRP1 Protein

Séquence: Gln22-Pro196

Attributs du produit: Recombinant Human PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-Pro196.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS ( pH 7.4).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))

Autre désignation: PGLYRP1 (PGLYRP1 Produits)

Synonymes: PGLYRP1 Protein, PGLYRP Protein, pgrp Protein, tag7 Protein, pgrps Protein, pglyrp Protein, pgrp-s Protein, tnfsf3l Protein, MGC108330 Protein, MGC108469 Protein, PGRP-SC1a Protein, si:dkey-113g17.4 Protein, si:ch211-202c21.3 Protein, PGRP Protein, PGRP-S Protein, PGRPS Protein, TAG7 Protein, TNFSF3L Protein, Pglyrp Protein, Tag7 Protein, Tasg7 Protein, Tnfsf3l Protein, Pgrp Protein, peptidoglycan recognition protein 1 Protein, peptidoglycan recognition protein 1 L homeolog Protein, peptidoglycan recognition protein 5 Protein, PGLYRP1 Protein, pglyrp1.L Protein, pglyrp1 Protein, pglyrp5 Protein, Pglyrp1 Protein

Sujet: Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.

Poids moléculaire: 46.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.

UniProt: O75594

Pathways: Activation of Innate immune Response