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RGMA Protein (AA 48-422) (His-Avi Tag,Biotin)

RGMA Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7275514
  • Antigène Voir toutes RGMA Protéines
    RGMA (RGM Domain Family, Member A (RGMA))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 48-422
    Origine
    • 8
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette RGMA protéine est marqué à la His-Avi Tag,Biotin.
    Fonction
    Biotinylated Human RGMa Protein
    Séquence
    Cys48-Gly422
    Attributs du produit
    Recombinant Biotinylated Human RGMa Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Cys48-Gly422.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product RGMA Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    RGMA (RGM Domain Family, Member A (RGMA))
    Autre désignation
    RGMa (RGMA Produits)
    Synonymes
    RGM Protein, BC059072 Protein, C230063O06 Protein, repulsive guidance molecule family member a Protein, repulsive guidance molecule family member A Protein, RGMA Protein, Rgma Protein
    Sujet
    Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its receptor neogenin regulates axon guidance, neuronal differentiation, and survival during the development of the CNS. RGMa induces T cell activation in experimental autoimmune encephalomyelitis (EAE), which is the animal model of multiple sclerosis (MS).
    Poids moléculaire
    44.5 kDa. Due to glycosylation, the protein migrates to 45-48 kDa based on Tris-Bis PAGE result.
    Pathways
    Tube Formation
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