SIRP-beta Protein (AA 30-369) (His-Avi Tag)

N° du produit ABIN7275656

Détail du produit

Antigène: SIRP-beta (SIRPB1A) (Signal-Regulatory Protein beta 1A (SIRPB1A))

Type de proteíne: Recombinant

Attributs du protein: AA 30-369

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SIRP-beta protéine est marqué à la His-Avi Tag.

Fonction: Human SIRP Beta/CD172b Protein

Séquence: Glu30-Ala369

Attributs du produit: Recombinant Human SIRP Beta/CD172b Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Ala369.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: SIRP-beta (SIRPB1A) (Signal-Regulatory Protein beta 1A (SIRPB1A))

Autre désignation: SIRP Beta (SIRPB1A Produits)

Synonymes: 9930027N05Rik Protein, SIRP-beta Protein, Sirpb Protein, Sirpb1 Protein, signal-regulatory protein beta 1A Protein, Sirpb1a Protein

Sujet: SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like sequence and two C1-set Ig domains.SIRP beta 1 is immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.

Poids moléculaire: 40 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.