SIRPB1 Protein (AA 30-371, Isoform 3) (His-Avi Tag,Biotin)

N° du produit ABIN7275661

Détail du produit

Antigène: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Type de proteíne: Recombinant

Attributs du protein: AA 30-371, Isoform 3

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SIRPB1 protéine est marqué à la His-Avi Tag,Biotin.

Fonction: Biotinylated Human SIRP Beta 1 Isoform 3 Protein

Séquence: Glu30-Leu371

Attributs du produit: Recombinant Biotinylated Human SIRP Beta 1 Isoform 3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Leu371.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Autre désignation: SIRP Beta 1 (SIRPB1 Produits)

Synonymes: CD172b Protein, SIRP-BETA-1 Protein, SIRPB1 Protein, SIRPG Protein, signal regulatory protein beta 1 Protein, signal-regulatory protein beta-1 Protein, signal-regulatory protein beta-1 isoform 3 Protein, SIRPB1 Protein, LOC458036 Protein, LOC458430 Protein, LOC485809 Protein, LOC715912 Protein, LOC100458151 Protein

Sujet: Signal regulatory protein β1 (SIRPB1) is a signal regulatory protein member of the immunoglobulin superfamily and is capable of modulating receptor tyrosine kinase-coupled signaling. Copy number variations at the SIRPB1 locus were previously reported to associate with prostate cancer aggressiveness in patients.SIRPB1 gene amplification and overexpression were detected in prostate cancer specimens. The knockdown of SIRPB1 significantly suppressed cell growth in colony formation assays and cell mobility.

Poids moléculaire: 39.9 kDa. Due to glycosylation, the protein migrates to 55-68 kDa based on Tris-Bis PAGE result.