IgG1 Protein (Asn317Phe-Mutant, Cys103Ser-Mutant, His316Lys-Mutant, Met135Tyr-Mutant, Ser137Thr-Mutant, Thr139Glu-Mutant) (His tag)

N° du produit ABIN7447926

Détail du produit

Antigène: IgG1

Type de proteíne: Recombinant

Attributs du protein: Asn317Phe-Mutant, Cys103Ser-Mutant, His316Lys-Mutant, Met135Tyr-Mutant, Ser137Thr-Mutant, Thr139Glu-Mutant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IgG1 protéine est marqué à la His tag.

Fonction: Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F) Protein, His Tag

Séquence: Glu 99 - Lys 330

Attributs du produit: Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F), His Tag is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (Accession # P01857-1 (C103S, M135Y, S137T, T139E, H316K, N317F).

Pureté: 95,00 %

niveau d'endotoxine: 1.0 EU per μg

Information d'application

Commentaires:

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.1 kDa. The protein migrates as 30-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: IgG1

Abstract: IgG1 Produits

Synonymes: IgG1 Protein, Igh-4 Protein, VH7183 Protein, immunoglobulin heavy constant gamma 1 (G1m marker) Protein, Ighg1 Protein

Classe de substances: Antibody

Sujet: Synonyms:IgG1,Description:Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.

Poids moléculaire: 28.1 kDa