Osteopontin Protein (AA 17-300) (His tag)
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- Antigène Voir toutes Osteopontin (SPP1) Protéines
- Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 17-300
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Origine
- Cynomolgus
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Osteopontin protéine est marqué à la His tag.
- Fonction
- Cynomolgus SPP1/OPN Protein
- Séquence
- Leu17-Asn300
- Attributs du produit
- Recombinant Cynomolgus SPP1/OPN Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu17-Asn300.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product SPP1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))
- Autre désignation
- SPP1 (SPP1 Produits)
- Synonymes
- BNSP Protein, BSPI Protein, ETA-1 Protein, OPN Protein, 2AR Protein, Apl-1 Protein, Bsp Protein, Eta Protein, OP Protein, Opn Protein, Opnl Protein, Ric Protein, Spp-1 Protein, OSP Protein, zgc:111821 Protein, secreted phosphoprotein 1 Protein, SPP1 Protein, Spp1 Protein, spp1 Protein
- Sujet
- Ovarian cancer is one of the most lethal malignant tumors in women. Secreted phosphoprotein 1 (SPP1) plays an important role in some cancer types. The expression of SPP1 was higher in epithelial ovarian cancer tissues than in normal ovarian tissues. Silencing SPP1 decreased the cell proliferation, migration, and invasion. Ectopic expression of SPP1 increased the cell proliferation, migration, and invasion. Silencing SPP1 prevented ovarian cancer growth in mice. Silencing SPP1 inhibited Integrin β1/FAK/AKT pathway.
- Poids moléculaire
- 33.16 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5WL90
- Pathways
- Regulation of Cell Size
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