ADAM15 Protein (Fc Tag)

N° du produit ABIN7490966

Détail du produit

Antigène: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ADAM15 protéine est marqué à la Fc Tag.

Fonction: Recombinant human ADAM15 protein with C-terminal human Fc tag

Specificité: ADAM15 (Leu18-Thr696) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Autre désignation: ADAM15 (ADAM15 Produits)

Synonymes: ADAM15 Protein, mdc15 Protein, MDC15 Protein, metargidin Protein, tMDCVI Protein, ADAM metallopeptidase domain 15 Protein, ADAM metallopeptidase domain 15 L homeolog Protein, a disintegrin and metallopeptidase domain 15 (metargidin) Protein, ADAM15 Protein, adam15.L Protein, adam15 Protein, Adam15 Protein

Sujet: ADAM 15, MDC-15
Description: The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 100.0 kDa after removal of the signal peptide. The apparent molecular mass of ADAM15-hFc is 100-130 kDa due to glycosylation.

UniProt: Q13444