CXCR3 Protein (mFc Tag)
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- Antigène Voir toutes CXCR3 Protéines
- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CXCR3 protéine est marqué à la mFc Tag.
- Fonction
- Recombinant human CXCR3 protein with C-terminal mouse Fc tag
- Specificité
- CXCR3 (Met1-Arg53) mFc (Pro99-Lys330)
- Attributs du produit
- Extracellular Domain Protein
- Pureté
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CXCR3 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
- Autre désignation
- CXCR3 (CXCR3 Produits)
- Synonymes
- CD182 Protein, CD183 Protein, CKR-L2 Protein, CMKAR3 Protein, GPR9 Protein, IP10-R Protein, Mig-R Protein, MigR Protein, Cd183 Protein, Cmkar3 Protein, CXCR3 Protein, cxcr3 Protein, Gpr9 Protein, CXC-R3 Protein, CXCR-3 Protein, zgc:92301 Protein, sb:eu378 Protein, C-X-C motif chemokine receptor 3 Protein, chemokine (C-X-C motif) receptor 3 Protein, chemokine (C-X-C motif) receptor 3, tandem duplicate 2 Protein, chemokine (C-X-C motif) receptor 3, tandem duplicate 1 Protein, CXCR3 Protein, Cxcr3 Protein, cxcr3 Protein, cxcr3.2 Protein, cxcr3.1 Protein
- Sujet
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CXC-R3, CXCR-3, CKR-L2, IP-10 receptor, CD183, GPR9
Description: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011] - Poids moléculaire
- predicted molecular mass of 32.1 kDa after removal of the signal peptide. The apparent molecular mass of CXCR3-mFc is 25-55 kDa due to glycosylation.
- UniProt
- P49682
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