BMP6 Protein (His tag)

N° du produit ABIN7491177

Détail du produit

Antigène: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette BMP6 protéine est marqué à la His tag.

Fonction: Recombinant human BMP6 protein with C-terminal 6xHis tag

Specificité: BMP6 (Cys21-His513) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Autre désignation: BMP6 (BMP6 Produits)

Synonymes: BMP6 Protein, zgc:113595 Protein, vgr Protein, vgr-1 Protein, vgr1 Protein, VGR Protein, VGR1 Protein, D13Wsu115e Protein, Vgr1 Protein, bone morphogenetic protein 6 Protein, bone morphogenetic protein 6 S homeolog Protein, BMP6 Protein, bmp6 Protein, bmp6.S Protein, Bmp6 Protein

Sujet: VGR, VGR1
Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]

Poids moléculaire: predicted molecular mass of 55.6 kDa after removal of the signal peptide. The apparent molecular mass of BMP6-His is 40-70 kDa due to glycosylation.

UniProt: P22004

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process