CCL3L1 Protein (His tag)

N° du produit ABIN7455627

Détail du produit

Antigène: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CCL3L1 protéine est marqué à la His tag.

Fonction: Recombinant Human C-C Motif Chemokine 3-Like 1 is produced by our Mammalian expression system and the target gene encoding Ala24-Ala93 is expressed with a 6His tag at the C-terminus.

Attributs du produit: Extracellular Domain Protein

Pureté: Greater than 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Stock: -20 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Autre désignation: CCL3L1 (CCL3L1 Produits)

Synonymes: 464.2 Protein, D17S1718 Protein, G0S19-2 Protein, LD78 Protein, LD78BETA Protein, MIP1AP Protein, SCYA3L Protein, SCYA3L1 Protein, C-C motif chemokine ligand 3 like 1 Protein, chemokine (C-C motif) ligand 3-like 1 Protein, CCL3L1 Protein

Sujet: C-C Motif Chemokine 3-Like 1, G0/G1 Switch Regulatory Protein 19-2, LD78-Beta(1-70), PAT 464.2, Small-Inducible Cytokine A3-Like 1, Tonsillar Lymphocyte LD78 Beta Protein, CCL3L1, D17S1718, G0S19-2, SCYA3L1, CCL3L3C-C Motif
Description: Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The processed form LD78-beta (3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. The copy number of this gene varies among individuals: most individuals have 1-6 copies in the diploid genome, although rare individuals have zero or more than six copies. The human genome reference assembly contains two full copies of the gene (CCL3L3 and CCL3L1) and a partial pseudogene. This record represents the more centromeric full-length gene.

Poids moléculaire: 8.82 KDa

UniProt: P16619

Pathways: Cellular Response to Molecule of Bacterial Origin