CCL18
(Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
Type de proteíne
Recombinant
Origine
Humain
Source
Escherichia coli (E. coli)
Purification/Conjugué
Cette CCL18 protéine est marqué à la His tag.
Fonction
Recombinant Human C-C Motif Chemokine 18 is produced by our E.coli expression system and the target gene encoding Ala21-Ala89 is expressed with a 6His tag at the N-terminus.
Attributs du produit
Extracellular Domain Protein
Pureté
Greater than 95 % as determined by reducing SDS-PAGE.
Crystallography grade
CCL18
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, WB, ELISA, Crys
Restrictions
For Research Use only
Format
Lyophilized
Buffer
a 0.2 μm filtered solution of PBS, 5 % Trehalose, pH 7.4.
Stock
-20 °C
Stockage commentaire
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Date de péremption
12 months
Antigène
CCL18
(Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
C-C Motif Chemokine 18, Alternative Macrophage Activation-Associated CC Chemokine 1, AMAC-1, CC Chemokine PARC, Dendritic Cell Chemokine 1, DC-CK1, Macrophage Inflammatory Protein 4, MIP-4, Pulmonary and Activation-Regulated Chemokine, Small-Inducible Cytokine A18, CCL18, AMAC1, DCCK1, MIP4, PARC, SCYA18 Description: C-C Motif Chemokine 18 (CCL18) is secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 is a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 may be involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It has chemotactic activity for naive T-cells, CD4 and CD8 T-cells and thus may play a role in both humoral and cell-mediated immunity responses.