CDH10 Protein (His tag)

N° du produit ABIN7491297

Détail du produit

Antigène: CDH10 (Cadherin 10, Type 2 (T2-Cadherin) (CDH10))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CDH10 protéine est marqué à la His tag.

Fonction: Recombinant Human CDH10 protein with C-terminal 6xHis tag

Specificité: CDH10 (Gly55-Ala613) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CDH10 (Cadherin 10, Type 2 (T2-Cadherin) (CDH10))

Autre désignation: CDH10 (CDH10 Produits)

Synonymes: A830016G23Rik Protein, C030003B10Rik Protein, C030011H18Rik Protein, cadherin 10 Protein, Cdh10 Protein, CDH10 Protein

Sujet: CAD10
Description: This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. Mutations in this gene may be associated with lung squamous cell carcinoma and colorectal cancer in human patients. [provided by RefSeq, Nov 2015]

Poids moléculaire: predicted molecular mass of 63.0 kDa after removal of the signal peptide. The apparent molecular mass of CDH10-His is 70-130 kDa due to glycosylation.

UniProt: Q9Y6N8

Pathways: Cell-Cell Junction Organization