Muscarinic Acetylcholine Receptor M2 Protein (Fc Tag)
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- Antigène Voir toutes Muscarinic Acetylcholine Receptor M2 (CHRM2) Protéines
- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Muscarinic Acetylcholine Receptor M2 protéine est marqué à la Fc Tag.
- Fonction
- Recombinant Human CHRM2 Protein with C-terminal human Fc tag
- Specificité
- CHRM2 (Met1-Glu22) hFc (Glu99-Ala330)
- Attributs du produit
- Extracellular Domain Protein
- Pureté
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CHRM2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
- Autre désignation
- CHRM2 (CHRM2 Produits)
- Synonymes
- HM2 Protein, AChR-M2 Protein, Chrm-2 Protein, M2 Protein, chrm2 Protein, Acm2 Protein, GPM2 Protein, cholinergic receptor muscarinic 2 Protein, cholinergic receptor, muscarinic 2, cardiac Protein, cholinergic receptor, muscarinic 2a Protein, cholinergic receptor, muscarinic 2 Protein, CHRM2 Protein, Chrm2 Protein, chrm2a Protein
- Sujet
- HM2The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
- Poids moléculaire
- predicted molecular mass of 28.6 kDa after removal of the signal peptide. The apparent molecular mass of CHRM2-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P08172
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