STEAP2 Protéine

N° du produit ABIN7491745

Détail du produit

Antigène: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human STEAP2 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Autre désignation: STEAP2 (STEAP2 Produits)

Synonymes: 4921538B17Rik Protein, AI930049 Protein, AW045895 Protein, IPCA-1 Protein, IPCA1 Protein, PCANAP1 Protein, STAMP1 Protein, STMP Protein, PUMPCn Protein, six transmembrane epithelial antigen of prostate 2 Protein, STEAP2 metalloreductase Protein, Steap2 Protein, STEAP2 Protein

Sujet: IPCA1, PCANAP1, PUMPCn, STAMP1, STMP
Description: This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Poids moléculaire: The human full length STEAP2 protein has a MW of 55.9 kDa

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis