Claudin 3 Protein (CLDN3)

N° du produit ABIN7491598

Détail du produit

Antigène: Claudin 3 (CLDN3)

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human CLDN3 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: Claudin 3 (CLDN3)

Autre désignation: CLDN3 (CLDN3 Produits)

Synonymes: claudin-3 Protein, cpe-r2 Protein, cpetr2 Protein, hrvp1 Protein, rvp1 Protein, CLDN3 Protein, LOC100228090 Protein, C7orf1 Protein, CPE-R2 Protein, CPETR2 Protein, HRVP1 Protein, RVP1 Protein, AI182374 Protein, Cpetr2 Protein, mRVP1 Protein, claudin 3 L homeolog Protein, claudin 3 Protein, claudin-4-like Protein, cldn3.L Protein, cldn3 Protein, CLDN3 Protein, LOC100228090 Protein, Cldn3 Protein

Sujet: C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]

Poids moléculaire: The human full length CLDN3 protein has a MW of 23.3 kDa

UniProt: O15551

Pathways: Hepatitis C