CXCR1 Protéine

N° du produit ABIN7491619

Détail du produit

Antigène: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human CXCR1 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Autre désignation: CXCR1 (CXCR1 Produits)

Synonymes: C-C Protein, C-C-CKR-1 Protein, CD128 Protein, CD181 Protein, CDw128a Protein, CKR-1 Protein, CMKAR1 Protein, IL8R1 Protein, IL8RA Protein, IL8RBA Protein, Il8ra Protein, CXCR-1 Protein, IL-8RA Protein, CXCR2 Protein, IL8RB Protein, cxcr1 Protein, cxcr2 Protein, C-X-C motif chemokine receptor 1 Protein, chemokine (C-X-C motif) receptor 1 Protein, C-X-C chemokine receptor type 1 Protein, C-X-C motif chemokine receptor 1 S homeolog Protein, CXCR1 Protein, Cxcr1 Protein, LOC100461947 Protein, cxcr1.S Protein

Sujet: C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA
Description: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]

Poids moléculaire: The human full length CXCR1 protein has a MW of 39.8 kDa

UniProt: P25024

Pathways: cAMP Metabolic Process