CXCR7 Protéine

N° du produit ABIN7491631

Détail du produit

Antigène: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human ACKR3 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Autre désignation: ACKR3 (CXCR7 Produits)

Synonymes: CMKOR1 Protein, CXC-R7 Protein, CXCR-7 Protein, CXCR7 Protein, GPR159 Protein, RDC-1 Protein, RDC1 Protein, AW541270 Protein, Cmkor1 Protein, Cxcr7 Protein, Rdc1 Protein, ackr3 Protein, cxcr7 Protein, rdc1 Protein, xcxcr7 Protein, atypical chemokine receptor 3 Protein, ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74 Protein, atypical chemokine receptor 3 L homeolog Protein, ACKR3 Protein, MmrVgp88 Protein, Ackr3 Protein, ackr3.L Protein

Sujet: CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1
Description: This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]

Poids moléculaire: The human full length ACKR3 protein has a MW of 41.3 kDa

UniProt: P25106

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling