TRPV1 Protéine

N° du produit ABIN7491753

Détail du produit

Antigène: TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human TRPV1 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))

Autre désignation: TRPV1 (TRPV1 Produits)

Synonymes: si:dkey-9e15.2 Protein, VR.5'sv Protein, Vr1 Protein, Vr1l1 Protein, VR1 Protein, OTRPC1 Protein, TRPV1alpha Protein, TRPV1beta Protein, VR-1 Protein, transient receptor potential cation channel, subfamily V, member 1 Protein, transient receptor potential cation channel subfamily V member 1 Protein, trpv1 Protein, Trpv1 Protein, TRPV1 Protein

Sujet: VR1
Description: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]

Poids moléculaire: The human full length TRPV1 protein has a MW of 94.8 kDa

UniProt: Q8NER1

Pathways: Dicarboxylic Acid Transport