CCR4 Protein-VLP

N° du produit ABIN7491560

Détail du produit

Antigène: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Type de proteíne: VLP

Origine: Humain

Source: HEK-293 Cells

Fonction: Human CCR4 full length protein-VLP

Attributs du produit: Full Length Transmembrane Proteins

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening

Commentaires:

Virus-like particles (VLPs) are self-assembling multi-protein nanoparticles with similar structural organization and conformation as viruses but without viral genome. The size of the VLP is about 100-150nm. It is secreted from the surface of the cells that express target membrane proteins (MPs). The purified VLPs have the target MPs inserted in a complete bilayer phospholipid membrane structure, mimic the natural membrane-penetrating state of the protein.
VLPs can be used for routine biochemical analysis, including ELISA, SPR affinity analysis, phage display screenings, protein labeling and cell binding experiments, Flow virometry analysis, etc. It can also be used as functional protein antigens to develop active antibodies with high drug potentials because the target protein on VLP exhibits a state like its native state on the cell surface.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in 1xPBS ( pH 7.4)

Stock: -80 °C

Stockage commentaire: The product should be stored at -80°C. Please do not repeated freeze-thaw cycles.

Détail du antigène

Antigène: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Autre désignation: CCR4 (CCR4 Produits)

Synonymes: CC-CKR-4 Protein, CD194 Protein, CKR4 Protein, CMKBR4 Protein, ChemR13 Protein, HGCN:14099 Protein, K5-5 Protein, Ccr4 Protein, C-C CKR-4 Protein, CHEMR1 Protein, Cmkbr4 Protein, LESTR Protein, Sdf1r Protein, C-C motif chemokine receptor 4 Protein, chemokine (C-C motif) receptor 4 Protein, CCR4 Protein, Ccr4 Protein

Sujet: CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4
Description: The protein belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Poids moléculaire: The human full length CCR4 Protein has a MW of 41.4 kDa

UniProt: P51679