IL31RA Protein (Fc Tag)

N° du produit ABIN7488885

Détail du produit

Antigène: IL31RA (Interleukin 31 Receptor A (IL31RA))

Type de proteíne: Recombinant

Origine: Cynomolgus, Macaque rhésus

Source: HEK-293 Cells

Purification/Conjugué: Cette IL31RA protéine est marqué à la Fc Tag.

Fonction: Cynomolgus/Rhesus macaque IL-31 RA Protein, Fc Tag

Séquence: Ala 20 - Glu 519

Attributs du produit: Cynomolgus/Rhesus macaque IL-31 RA Protein, Fc Tag (ILA-H525b) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 519 (Accession # XP_005556977.2).

Pureté: 90 %

niveau d'endotoxine: 1.0 EU per μg

Information d'application

Commentaires:

This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 84.5 kDa. The protein migrates as 110-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: IL31RA (Interleukin 31 Receptor A (IL31RA))

Autre désignation: IL-31 RA (IL31RA Produits)

Synonymes: IL31RA Protein, CRL Protein, CRL3 Protein, GLM-R Protein, GLMR Protein, GPL Protein, IL-31RA Protein, PLCA2 Protein, PRO21384 Protein, hGLM-R Protein, Glmr Protein, NR10 Protein, interleukin 31 receptor A Protein, IL31RA Protein, Il31ra Protein

Sujet: Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.

Poids moléculaire: 84.5 kDa

NCBI Accession: XP_005556977