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Claudin 6 Protein (CLDN6) (His tag,Twin-Strep tag)

CLDN6 Origine: Humain Hôte: Cellules d'insectes Recombinant 80 %
N° du produit ABIN7488889
  • Antigène Voir toutes Claudin 6 (CLDN6) Protéines
    Claudin 6 (CLDN6)
    Type de proteíne
    Recombinant
    Origine
    • 12
    • 2
    • 1
    Humain
    Source
    • 10
    • 2
    • 2
    • 1
    Cellules d'insectes
    Purification/Conjugué
    Cette Claudin 6 protéine est marqué à la His tag,Twin-Strep tag.
    Fonction
    Human Claudin-6 / CLDN6 Protein, His,Twin-Strep Tag (Detergent)
    Séquence
    Ala 2 - Val 220
    Attributs du produit
    Human Claudin-6 Protein, His,Twin-Strep Tag is expressed from Baculovirus-Insect cells. It contains AA Ala 2 - Val 220 (Accession # P56747-1).
    Pureté
    80 %
    niveau d'endotoxine
    1.0 EU per μg
    Top Product
    Discover our top product CLDN6 Protéine
  • Commentaires

    This protein carries a polyhistidine tag at the N-terminus and a twin strep tag at the C-terminus. (10xHis , Twin-Strep) The protein has a calculated MW of 28.3 kDa. The protein migrates as 26-27 kDa under reducing (R) condition (SDS-PAGE).

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    50 mM HEPES, 150 mM NaCl, DDM, CHS, pH 7.5
    Stock
    -80 °C
    Stockage commentaire
    -70°C
  • Antigène
    Claudin 6 (CLDN6)
    Autre désignation
    Claudin-6 (CLDN6 Produits)
    Synonymes
    cldn4l2 Protein, cldn6 Protein, CLDN6 Protein, AL024037 Protein, claudin 6, gene 1 L homeolog Protein, claudin 6 Protein, cldn6.1.L Protein, CLDN6 Protein, Cldn6 Protein
    Sujet
    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. Claudin-6, also knows as CLDN6, is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. And it is one of the entry cofactors for hepatitis C virus. The methylation of CLDN6 may be involved in esophageal tumorigenesis. The gene of CLDN6 is adjacent to another family member CLDN9 on chromosome 16.
    Poids moléculaire
    28.3 kDa
    Pathways
    Hepatitis C
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