LRP1 Protein (Fc Tag)

N° du produit ABIN7482511

Détail du produit

Antigène: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette LRP1 protéine est marqué à la Fc Tag.

Fonction: Human LRP-1 / cluster II Protein, Fc Tag (MALS verified)

Séquence: Arg 786 - Leu 1165

Attributs du produit: Human cluster II Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Arg 786 - Leu 1165 (Accession # Q07954-1).

Pureté: 95 %

niveau d'endotoxine: 0.1 EU per μg

Classe de qualité: MALS verified

Information d'application

Commentaires:

This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 68.0kDa. The protein migrates as 75-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Autre désignation: LRP-1 (LRP1 Produits)

Synonymes: A2MR Protein, APOER Protein, APR Protein, CD91 Protein, IGFBP3R Protein, LRP Protein, LRP1A Protein, TGFBR5 Protein, A2mr Protein, AI316852 Protein, Lrp Protein, LRP-1 Protein, LDL receptor related protein 1 Protein, prolow-density lipoprotein receptor-related protein 1 Protein, low density lipoprotein receptor-related protein 1 Protein, LRP1 Protein, Lrp1 Protein, LOC100414789 Protein

Sujet: Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membrane of cells. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor. LRP1 is also a key signalling protein and, thus, involved in various biological processes, such as lipoprotein metabolism and cell motility, and diseases, such as neurodegenerative diseases, atherosclerosis, and cancer.

Poids moléculaire: 68.0kDa

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling