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Claudin 4 Protein-VLP (CLDN4) (AA 1-209)

CLDN4 Origine: Humain Hôte: HEK-293 Cells VLP > 95 % as determined by HPLC
N° du produit ABIN7504302
  • Antigène Voir toutes Claudin 4 (CLDN4) Protéines
    Claudin 4 (CLDN4)
    Type de proteíne
    VLP
    Attributs du protein
    AA 1-209
    Origine
    • 9
    • 2
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Fonction
    Human Claudin 4 Protein-VLP
    Séquence
    Met1-Val209
    Attributs du produit
    Recombinant Human Claudin 4 Protein-VLP is expressed from HEK293.It contains Met1-Val209.
    Pureté
    > 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product CLDN4 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
    Stock
    -80 °C
    Stockage commentaire
    Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Claudin 4 (CLDN4)
    Autre désignation
    Claudin 4 (CLDN4 Produits)
    Synonymes
    CPE-R Protein, CPER Protein, CPETR Protein, CPETR1 Protein, WBSCR8 Protein, hCPE-R Protein, Cep-r Protein, Cpetr Protein, Cpetr1 Protein, CLDN4 Protein, cper Protein, cpe-r Protein, cpetr Protein, cpetr1 Protein, hcpe-r Protein, wbscr8 Protein, claudin 4 Protein, claudin 4 L homeolog Protein, CLDN4 Protein, Cldn4 Protein, cldn4 Protein, cldn4.L Protein
    Sujet
    Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.
    Poids moléculaire
    23.31 kDa.
    UniProt
    O14493
    Pathways
    Hepatitis C
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