IL1F10 Protein (AA 1-152) (His tag)

N° du produit ABIN7504439

Détail du produit

Antigène: IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))

Type de proteíne: Recombinant

Attributs du protein: AA 1-152

Origine: Humain

Source: Levure

Purification/Conjugué: Cette IL1F10 protéine est marqué à la His tag.

Fonction: Human IL-1F10/IL-38 Protein

Séquence: Met1-Trp152

Attributs du produit: Recombinant Human IL-1F10/IL-38 Protein is expressed from Yeast with His tag at the C-terminus.It contains Met1-Trp152.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))

Autre désignation: IL-1F10 (IL1F10 Produits)

Synonymes: FIL1-theta Protein, IL-1HY2 Protein, IL-38 Protein, IL1-theta Protein, IL1HY2 Protein, interleukin 1 family, member 10 Protein, interleukin 1 family member 10 Protein, Il1f10 Protein, IL1F10 Protein

Sujet: Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory function by binding to several receptors, including interleukin-36 receptor (IL-36R), interleukin-1 receptor accessory protein-like 1 (IL-1RAPL1), and interleukin-1 receptor 1 (IL-1R1) to block binding with other pro-inflammatory cytokines and inhibit subsequent signaling pathways, thereby regulating the differentiation and function of T cells, peripheral blood mononuclear cells, macrophages, and dendritic cells.

Poids moléculaire: 18.07 kDa. Due to glycosylation, the protein migrates to 20-23 kDa based on Tris-Bis PAGE result.