Osteomodulin Protein (OMD) (AA 21-421) (His tag)

N° du produit ABIN7504495

Détail du produit

Antigène: Osteomodulin (OMD)

Type de proteíne: Recombinant

Attributs du protein: AA 21-421

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Osteomodulin protéine est marqué à la His tag.

Fonction: Human Osteomodulin Protein

Séquence: Gln21-Glu421

Attributs du produit: Recombinant Human Osteomodulin Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln21-Glu421.

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Osteomodulin (OMD)

Autre désignation: Osteomodulin (OMD Produits)

Synonymes: si:ch211-103f16.5 Protein, OMD Protein, OSAD Protein, SLRR2C Protein, osteomodulin Protein, omd Protein, OMD Protein, Omd Protein

Sujet: Osteomodulin (OMD) is a member of the small leucine-rich repeat proteoglycan family, which is involved in the organization of the extracellular matrix. OMD is located in bone tissue and is reportedly important for bone mineralization. Mechanistically, OMD could bind to BMP2 via its terminal leucine-rich repeats and formed complexes with BMP2 and its membrane receptors, thus promoting BMP/SMAD signal transduction. In addition, OMD was a putative target gene of SMAD4, which plays a pivotal role in this pathway.

Poids moléculaire: 48.25 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.

UniProt: Q99983

Pathways: Glycosaminoglycan Metabolic Process