Uromodulin Protein (UMOD) (AA 25-587) (His tag)

N° du produit ABIN7505005

Détail du produit

Antigène: Uromodulin (UMOD)

Type de proteíne: Recombinant

Attributs du protein: AA 25-587

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Uromodulin protéine est marqué à la His tag.

Séquence: Asp25-Phe587

Attributs du produit: A DNA sequence encoding theHuman THP protein (P07911) (Asp25-Phe587) was expressed with a N-His.

Pureté: >85 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Uromodulin (UMOD)

Autre désignation: THP (UMOD Produits)

Synonymes: ADMCKD2 Protein, FJHN Protein, HNFJ Protein, HNFJ1 Protein, MCKD2 Protein, THGP Protein, THP Protein, urehr4 Protein, uromodulin Protein, UMOD Protein, Umod Protein

Sujet:

Background: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF.Facilitates neutrophil migration across renal epithelia.

Synonym: Tamm-Horsfall urinary glycoprotein

Poids moléculaire: 61.4 kDa

UniProt: P07911