NKp44/NCR2 Protein (AA 1-190) (His tag)
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- Antigène Voir toutes NKp44/NCR2 (NCR2) Protéines
- NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-190
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette NKp44/NCR2 protéine est marqué à la His tag.
- Séquence
- Met 1-Pro 190
- Attributs du produit
- A DNA sequence encoding the human NCR2 (NP_004819.2) extracellular domain (Met 1-Pro 190) was fused with a polyhistidine tag at the C-terminus.
- Pureté
- >88 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- <1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product NCR2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))
- Autre désignation
- NCR2 (NCR2 Produits)
- Synonymes
- CD336 Protein, LY95 Protein, NK-p44 Protein, NKP44 Protein, dJ149M18.1 Protein, uncharacterized LOC609023 Protein, natural cytotoxicity triggering receptor 2 Protein, LOC609023 Protein, NCR2 Protein
- Sujet
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Background: Natural cytotoxicity triggering receptor 2 (NCR2), also known as Natural killer cell p44-related protein (NKp44), or CD336, is a member of the natural cytotoxicity receptor (NCR) family, which composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. It is a novel transmembrane glycoprotein belonging to the Immunoglobulin superfamily characterized by a single extracellular V-type domain. The cytoplasmic domain of NKp44 also contains a sequence that matches the immunoreceptor tyrosine-based inhibitory motif (ITIM) consensus. This Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp44 is selectively expressed by IL-2-activated NK cells and may contribute to the increased efficiency of activated NK cells to mediate tumor cell lysis. Tumor cell recognition of the mutated NKp44 proteins was significantly reduced and correlated with their lower recognition of heparin.
Synonym: CD336,dJ149M18.1,LY95,NK-p44,NKP44,RP1-149M18.2
- Poids moléculaire
- 20 kDa
- UniProt
- O95944
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