CEACAM3 Protein (His tag)

N° du produit ABIN7534052

Détail du produit

Antigène: CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CEACAM3 protéine est marqué à la His tag.

Fonction: Active Recombinant Human CEACAM3/CD66d Protein

Séquence: MGPPSASPHR ECIPWQGLLL TASLLNFWNP PTTAKLTIES MPLSVAEGKE VLLLVHNLPQ HLFGYSWYKG ERVDGNSLIV GYVIGTQQAT PGAAYSGRET IYTNASLLIQ NVTQNDIGFY TLQVIKSDLV NEEATGQFHV YQENAPGLPV GAVAG

Specificité: Met1-Gly155

Pureté: > 92 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Human CEACAM3 at 1μg/mL (100 μL/well) can bind CEACAM3 Mouse mAb with a linear range of 0.1-2.7 ng/mL.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))

Autre désignation: CEACAM3/CD66d (CEACAM3 Produits)

Synonymes: CD66D Protein, CEA Protein, CGM1 Protein, W264 Protein, W282 Protein, CGM4AA Protein, Cea Protein, Ceacam5 Protein, Cear Protein, Cgm1 Protein, Cgm4 Protein, RATCEAA Protein, RATCGM4AA Protein, EG384557 Protein, Psg24 Protein, cea12 Protein, carcinoembryonic antigen related cell adhesion molecule 3 Protein, carcinoembryonic antigen-related cell adhesion molecule 3 Protein, CEACAM3 Protein, Ceacam3 Protein

Sujet:

Description: The protein encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.

Name: CEACAM3,CD66D,CEA,CGM1,W264,W282

ID gène: 1084

UniProt: P40198