CD5L Protein (His tag)

N° du produit ABIN7519798

Détail du produit

Antigène: CD5L (CD5 Molecule-Like (CD5L))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CD5L protéine est marqué à la His tag.

Fonction: Recombinant Human CD5L Protein

Séquence: SPSGVRLVGG LHRCEGRVEV EQKGQWGTVC DDGWDIKDVA VLCRELGCGA ASGTPSGILY EPPAEKEQKV LIQSVSCTGT EDTLAQCEQE EVYDCSHDED AGASCENPES SFSPVPEGVR LADGPGHCKG RVEVKHQNQW YTVCQTGWSL RAAKVVCRQL GCGRAVLTQK RCNKHAYGRK PIWLSQMSCS GREATLQDCP SGPWGKNTCN HDEDTWVECE DPFDLRLVGG DNLCSGRLEV LHKGVWGSVC DDNWGEKEDQ VVCKQLGCGK SLSPSFRDRK CYGPGVGRIW LDNVRCSGEE QSLEQCQHRF WGFHDCTHQE DVAVICSG

Specificité: Ser20-Gly347

Pureté: > 92 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Concentration: 0.61 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: CD5L (CD5 Molecule-Like (CD5L))

Autre désignation: CD5L (CD5L Produits)

Synonymes: AIM Protein, API6 Protein, PRO229 Protein, SP-ALPHA Protein, Spalpha Protein, 1/6 Protein, AAC-11 Protein, AI047839 Protein, Api6 Protein, CT2 Protein, Pdp Protein, Sp-alpha Protein, CD5L Protein, CD5 molecule like Protein, CD5 antigen-like Protein, Cd5 molecule-like Protein, CD5 molecule-like Protein, scavenger receptor cysteine-rich domain superfamily protein-like Protein, CD5L Protein, Cd5l Protein, LOC100375137 Protein

Sujet:

Description: CD5L (CD5 antigen-like), also known as Sp alpha and AIM, is a 50 kDa secreted glycoprotein that belongs to the SRCR (scavenger receptor cysteine rich) group B family of proteins. CD5L is up-regulated in macrophages at inflammatory sites. It sustains inflammatory reactions by both increasing the phagocytic capacity of macrophages and impeding the apoptosis of local macrophages, NK cells, and T cells. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. In the thymic cortex, CD5L protects cortical CD4+CD8+thymocytes from apoptosis. CD5L circulates in the serum in complex with IgM.

Name: CD5L,AIM,API6,CT-2,PRO229,SP-ALPHA,Spalpha,hAIM

ID gène: 922

UniProt: O43866