IL1F9 Protéine

N° du produit ABIN7520123

Détail du produit

Antigène: IL1F9 (Interleukin 1 Family Member 9 (IL1F9))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Active Recombinant Human IL36 gamma/IL-1F9 Protein

Séquence: SMCKPITGTI NDLNQQVWTL QGQNLVAVPR SDSVTPVTVA VITCKYPEAL EQGRGDPIYL GIQNPEMCLY CEKVGEQPTL QLKEQKIMDL YGQPEPVKPF LFYRAKTGRT STLESVAFPD WFIASSKRDQ PIILTSELGK SYNTAFELNI ND

Specificité: Ser18-Asp169

Pureté: > 92 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: 1.The NF-kB (Luc) HEK293 Reporter Cell was stimulated with serial dilutions of human IL-36 gamma protein. After 7 hours, 2.5 ng/mL of human IL-36 gamma can effectively activate the NF-κB signaling.|2.Measured by its ability to induce IL-8 secretion in A431 human epithelial carcinoma cells. The ED₅₀ for for this effect is 101.34-405.36 ng/mL.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: IL1F9 (Interleukin 1 Family Member 9 (IL1F9))

Autre désignation: IL36 gamma/IL-1F9 (IL1F9 Produits)

Synonymes: IL-1F9 Protein, IL-1H1 Protein, IL-1RP2 Protein, IL1E Protein, IL1F9 Protein, IL1H1 Protein, IL1RP2 Protein, Il36g Protein, Il1f9 Protein, RGD1563019 Protein, IL36G Protein, interleukin 36 gamma Protein, interleukin 1 family, member 9 Protein, interleukin 36, gamma Protein, interleukin-36 gamma Protein, IL36G Protein, Il1f9 Protein, Il36g Protein, LOC100065031 Protein

Sujet:

Description: The protein is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection.

Name: IL36G,IL-1F9,IL-1H1,IL-1RP2,IL1E,IL1F9,IL1H1,IL1RP2

ID gène: 56300

UniProt: Q9NZH8