IL36A/IL1F6 Protein (His tag)

N° du produit ABIN7533752

Détail du produit

Antigène: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette IL36A/IL1F6 protéine est marqué à la His tag.

Fonction: Recombinant Human IL-36 alpha/IL-1F6 Protein

Séquence: MEKALKIDTP QQGSIQDINH RVWVLQDQTL IAVPRKDRMS PVTIALISCR HVETLEKDRG NPIYLGLNGL NLCLMCAKVG DQPTLQLKEK DIMDLYNQPE PVKSFLFYHS QSGRNSTFES VAFPGWFIAV SSEGGCPLIL TQELGKANTT DFGLTMLF

Specificité: Met1-Phe158

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 1.0 EU/μg of the protein by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Autre désignation: IL-36 alpha/IL-1F6 (IL1F6 Produits)

Synonymes: Il1f6 Protein, Fil1 Protein, IL-1H1 Protein, IL1RP2 Protein, Il1f9 Protein, Il36a Protein, FIL1 Protein, FIL1(EPSILON) Protein, FIL1E Protein, IL-1F6 Protein, IL1(EPSILON) Protein, IL1F6 Protein, interleukin 36, alpha Protein, interleukin 1 family, member 6 (epsilon) Protein, interleukin 1 family, member 6 Protein, interleukin 36 alpha Protein, Il36a Protein, IL1F6 Protein, IL36A Protein, Il1f6 Protein

Sujet:

Description: Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine which plays an important role in innate and adaptive immunity.IL-1F6 can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this protein has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.

Name: IL36A,FIL1,FIL1(EPSILON),FIL1E,IL-1F6,IL1(EPSILON),IL1F6

ID gène: 27179

UniProt: Q9UHA7

Pathways: Cancer Immune Checkpoints