IL22RA2 Protein (His tag)
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- Antigène Voir toutes IL22RA2 Protéines
- IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL22RA2 protéine est marqué à la His tag.
- Fonction
- Active Recombinant Human IL-22RA2/IL22BP Protein
- Séquence
- TQSTHESLKP QRVQFQSRNF HNILQWQPGR ALTGNSSVYF VQYKIYGQRQ WKNKEDCWGT QELSCDLTSE TSDIQEPYYG RVRAASAGSY SEWSMTPRFT PWWETKIDPP VMNITQVNGS LLVILHAPNL PYRYQKEKNV SIEDYYELLY RVFIINNSLE KEQKVYEGAH RAVEIEALTP HSSYCVVAEI YQPMLDRRSQ RSEERCVEIP
- Specificité
- Thr22-Pro231
- Pureté
- > 90 % by SDS-PAGE.
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized recombinant Human IL22 at 2 μg/mL (100 μL/well) can bind recombinant Human IL22BP, the EC50 of Human IL22BP is 10.78 ng/mL.
- Top Product
- Discover our top product IL22RA2 Protéine
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Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 22-231) protein (His tag)
IL22RA2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 22-263) protein (His tag)Crystallography grade IL22RA2 Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 21-230) protein (His tag)Crystallography grade IL22RA2 Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Antigène
- IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))
- Autre désignation
- IL-22RA2/IL22BP (IL22RA2 Produits)
- Synonymes
- CRF2-10 Protein, CRF2-S1 Protein, CRF2X Protein, IL-22BP Protein, IL-22R-alpha-2 Protein, IL-22RA2 Protein, ZCYTOR16 Protein, CRF2-s1 Protein, Il-22bp Protein, Crf2-s1 Protein, interleukin 22 receptor subunit alpha 2 Protein, interleukin 22 receptor, alpha 2 Protein, IL22RA2 Protein, Il22ra2 Protein
- Sujet
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Description: Interleukin 22 binding protein (IL-22BP), also known as CRF2-10, CRF2-X, and IL-22RA2, is a 35-45 kDa secreted glycoprotein in the type II cytokine receptor family (CRF). IL-22BP specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor.IL-22BP is produced by dendritic cells (DC), epithelial cells, activated B cells, and activated monocytes. It is constitutively expressed by DC but is down-regulated during local inflammation and in response to tissue damage. IL-22BP is critical for limiting IL-22 induced epithelial cell proliferation during wound healing, and its deficiency can enable uncontrolled proliferation and enhance tumor development.
Name: IL22RA2,CRF2-10,CRF2-S1,CRF2X,IL-22BP,IL-22R-alpha-2,IL-22RA2,ZCYTOR16
- ID gène
- 116379
- UniProt
- Q969J5-2
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