TLR4 Protein (AA 24-839)

N° du produit ABIN7866072

Cette protéine Recombinant TLR4 est produite dans CHO Cells.

Aperçu rapide pour TLR4 Protein (AA 24-839) (ABIN7866072)

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: CHO Cells

Pureté: >95 % , as determined by SDS-PAGE and HPLC

Détail du produit

Attributs du protein: AA 24-839

Fonction: Human TLR4 Protein Recombinant

Séquence: ESWEPCVEVV PNITYQCMEL NFYKIPDNLP FSTKNLDLSF NPLRHLGSYS FFSFPELQVL DLSRCEIQTI EDGAYQSLSH LSTLILTGNP IQSLALGAFS GLSSLQKLVA VETNLASLEN FPIGHLKTLK ELNVAHNLIQ SFKLPEYFSN LTNLEHLDLS SNKIQSIYCT DLRVLHQMPL LNLSLDLSLN PMNFIQPGAF KEIRLHKLTL RNNFDSLNVM KTCIQGLAGL EVHRLVLGEF RNEGNLEKFD KSALEGLCNL TIEEFRLAYL DYYLDDIIDL FNCLTNVSSF SLVSVTIERV KDFSYNFGWQ HLELVNCKFG QFPTLKLKSL KRLTFTSNKG GNAFSEVDLP SLEFLDLSRN GLSFKGCCSQ SDFGTTSLKY LDLSFNGVIT MSSNFLGLEQ LEHLDFQHSN LKQMSEFSVF LSLRNLIYLD ISHTHTRVAF NGIFNGLSSL EVLKMAGNSF QENFLPDIFT ELRNLTFLDL SQCQLEQLSP TAFNSLSSLQ VLNMSHNNFF SLDTFPYKCL NSLQVLDYSL NHIMTSKKQE LQHFPSSLAF LNLTQNDFAC TCEHQSFLQW IKDQRQLLVE VERMECATPS DKQGMPVLSL NITCQMNKT

Attributs du produit:

Protein Size: Recombinant TLR4 migrates as an approximately 67 kDa protein due to glycosylation under reducing conditions in SDS-PAGE.

Sequence Position: Optimized DNA sequence encoding Human TLR4 mature chain was expressed in CHO. Recombinant Human Toll-like receptor 4 encodes amino acid residues 24-839.

niveau d'endotoxine: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg(1EU/μg).

Biological Activity Comment: Determined by its ability to bind rhMD-2 in a functional ELISA.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Buffer: TLR4 was Lyophilized from PBS, pH 7.2.

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Upon reconstitution, this product can be stored in working aliquots at 2°- 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Date de péremption: 24 months

Détail du antigène

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Autre désignation: TLR4

Poids moléculaire: 67 kDa

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins