IL-3 Protéine

N° du produit ABIN7866454

Cette protéine Recombinant IL-3 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour IL-3 Protéine (ABIN7866454)

Antigène: IL-3 (Interleukin 3 (IL-3))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: >98 % by SDS-PAGE

Détail du produit

Fonction: Recombinant Human IL-3 Protein

Séquence: MAPMTQTTPL KTSWVNCSNM IDEIITHLKQ PPLPLLDFNN LNGEDQDILM ENNLRRPNLE AFNRAVKSLQ NASAIESILK NLLPCLPLAT AAPTRHPIHI KDGDWNEFRR KLTFYLKTLE NAQAQQTTLS LAIF

Specificité: Chromosomal location:5q31.1

Attributs du produit: Length (aa):134

niveau d'endotoxine: < 0.1 ng/μg of protein (< 1EU/μg)

Information d'application

Indications d'application: The ED50 as determined by the dose-dependent stimulation of the proliferation of TF-1 cells is < 0.1 - 0.5 ng/mL. The WHO standard #91/510 was used as a control.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: water,The lyophilized IL-3 should be reconstituted in water to a concentration not less than 100 μg/mL. This solution can be diluted into other buffered solutions or stored at -20 °C for future use.

Buffer: PBS

Stock: 0 °C,-20 °C

Stockage commentaire: The lyophilized IL-3, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted IL-3 should be stored in working aliquots at -20°C.

Détail du antigène

Antigène: IL-3 (Interleukin 3 (IL-3))

Autre désignation: IL-3

Sujet:

Synonyms: IL3, IL-3, MCGF, MULTI-CSF

Description: IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.

Poids moléculaire: 15.0 kDa

ID gène: 3562

NCBI Accession: NM_000588, NP_000579

UniProt: P08700

Pathways: Signalistation JAK/STAT, Regulation of Carbohydrate Metabolic Process, Autophagy