IL-1 beta Protéine
Aperçu rapide pour IL-1 beta Protéine (ABIN7956067)
Antigène
Voir toutes IL-1 beta (IL1B) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Fonction
- Recombinant Rhesus Macaque Interleukin-1 beta
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Séquence
- APVRSLHCTL RDAQLKSLVM SGPYELKALH LQGQDLEQQV VFSMSFVQGE ESNDKIPVAL GLKAKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTRGG QDITDFTMQF VSS
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 1 EU/ug of rRhIL-1β as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10.G4.1 cells is less than 10 pg/ml, corresponding to a specific activity of > 1.0 x108 IU/mg.
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Commentaires
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Approximately 17.3 kDa, a single non-glycosylated polypeptide chain containing 153 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Date de péremption
- 12 months
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Autre désignation
- Interleukin-1 beta
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Poids moléculaire
- 17.3 kDa
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ID gène
- 704701
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UniProt
- P48090
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Pathways
- Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
Antigène
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