IL-6 Protéine
Aperçu rapide pour IL-6 Protéine (ABIN7956075)
Antigène
Voir toutes IL-6 (IL6) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Fonction
- Recombinant Rhesus Macaque Interleukin-6
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Séquence
- MAPVLPGEDS KNVAAPHSQP LTSSERIDKH IRYILDGISA LRKETCNRSN MCESSKEALA ENNLNLPKMA EKDGCFQSGF NEDTCLVKII TGLLEFEVYL EYLQNRFESS EEQARAVQMS TKVLIQFLQK KAKNLDAITT PEPTTNASLL TKLQAQNQWL QDMTTHLILR SFKEFLQSNL RALRQM
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 1 EU/ug of rRhIL-6 as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay usingIL-6-dependent murine 7TD1 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 x107 IU/mg.
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Commentaires
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Approximately 21.1 kDa, a single non-glycosylated polypeptide chain containing 186 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in 50 mM Tris-HCl, pH 9.0, 600 mM NaCl, with 0.02 % Tween-20.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Date de péremption
- 12 months
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- IL-6 (IL6) (Interleukin 6 (IL6))
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Autre désignation
- Interleukin-6
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Poids moléculaire
- 21.1 kDa
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Pathways
- Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Antigène
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