IL-6 Protéine
Aperçu rapide pour IL-6 Protéine (ABIN7956098)
Antigène
Voir toutes IL-6 (IL6) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Fonction
- Recombinant Murine Interleukin-6
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Séquence
- MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 1 EU/ug of rMuIL-6 as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is less than 0.02 ng/ml, corresponding to a specific activity of > 5 x107 IU/mg.
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Commentaires
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Approximately 21.7 kDa, a single non-glycosylated polypeptide chain containing 188 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered solution in 30 mM Acetic Acid, pH 3.0, 150 mM NaCl, 5 % Trehalose, 0.02 % Tween-20.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Date de péremption
- 12 months
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- IL-6 (IL6) (Interleukin 6 (IL6))
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Autre désignation
- Interleukin-6
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Poids moléculaire
- 21.7 kDa
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ID gène
- 16193
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UniProt
- P08505
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Pathways
- Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Antigène
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