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Human Monoclonal TWF1 Primary Antibody pour ICC, FACS - ABIN1098116
Rajaraman, Brenner, Neta, Pfeiffer, Wang, Yeager, Thomas, Fine, Linet, Rothman, Chanock, Inskip: Risk of meningioma and common variation in genes related to innate immunity. dans Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010
Show all 2 Pubmed References
Human Monoclonal TWF1 Primary Antibody pour IHC (p), IP - ABIN562523
Ambs, Prueitt, Yi, Hudson, Howe, Petrocca, Wallace, Liu, Volinia, Calin, Yfantis, Stephens, Croce: Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer. dans Cancer research 2008
TWF1 and VIM (Montrer VIM Anticorps) are required for miR (Montrer MLXIP Anticorps)-30c to regulate breast cancer cell invasion.
An interleukin-6 (Montrer IL6 Anticorps) family member, interleukin-11 (Montrer IL11 Anticorps) is identified as a secondary target of twinfilin 1 in the microRNA-30c signalling pathway.
These data suggest that the association with an actin monomer induces a first-order conformational change within the twinfilin molecule.
mammals have two twinfilin isoforms, which are differentially expressed and regulated through distinct cellular signaling pathways
FGF signaling promotes the expansion of A6-expressing liver cells partly via AKT (Montrer AKT1 Anticorps)-dependent activation of beta-Catenin (Montrer CTNNB1 Anticorps) expansion of A6(+ive) periportal cells and possibly by reprogramming of centrolobular hepatocytes.
structural conservation between its actin monomer-binding sites and the binding site of actin-depolymerizing factor (ADF)/cofilin (Montrer CFL1 Anticorps)
a novel model for how sequential interactions between actin monomers, twinfilin, capping protein, and actin filaments promote cytoskeletal dynamics
The crystal structure of twinfilin's C-terminal ADF-H domain in complex with an actin monomer, is presented.
like Twf1, mouse Twf2 (Montrer TWF2 Anticorps) is a filament barbed-end capping protein, and that two tissue-specific and biochemically distinct isoforms are generated from the Twf2 (Montrer TWF2 Anticorps) gene through alternative promoter usage
The results reveal that TWF1 is highly induced by the stimulation of amino acids and hormones and involved in regulation of milk bio-synthesis and cell proliferation via the mTOR (Montrer FRAP1 Anticorps) pathway in bovine mammary epithelial cells.
Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity).
A6 protein tyrosine kinase
, PTK9 protein tyrosine kinase 9
, protein A6
, protein tyrosine kinase 9
, twinfilin, actin-binding protein, homolog 1
, actin monomer-binding protein
, twinfilin 1
, LOW QUALITY PROTEIN: twinfilin-1
, twinfilin, actin-binding protein, homolog 1b