Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher tous les synonymes
Sélectionnez vos espèces d'intérêt
Autosomal recessive agammaglobulinemia associated with an IGLL1 gene missense mutation.
Irrespective of subtype, Acute Lymphoblastic Leukemia with high levels of IGHM, IGLL1 and VPREB1 are arrested at the pre-B stage and correlate with good prognosis in high-risk pediatric B-cell precursor acute lymphoblastic leukemia.
Hhydrophobic residues from the lambda5-UR is crucial for the interaction with GAL1 and for pre-BCR clustering.
the non-Ig part of lambda5 crosslinks precursor b-cell receptors for downregulation and stimulation.
lambda5 differentially relies on the lambda-like Ig and unique region to probe H chain structure to best accommodate diversity among H chains.
Reduced surrogate light chain expression contributes to decreased production of pre-B lymphocytes in aged bone marrow and in young lambda5 gene knockout mice.
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
CD179 antigen-like family member B
, CD179b antigen
, Pre-B lymphocyte-specific protein-2
, ig lambda-5
, immunoglobulin omega polypeptide chain
, immunoglobulin-related 14.1 protein
, immunoglobulin-related protein 14.1
, Ig lambda chain V-1 region
, Ig light chain variable region
, immunoglobulin lambda-like polypeptide 1
, Immunoglobulin lambda-like polypeptide 1-like
, immunoglobulin lambda chain 5
, lambda 5