Aperçu des produits pour anti-ADRBK2 (ADRBK2) Anticorps

Full name:: anti-Adrenergic, Beta, Receptor Kinase 2 Anticorps (ADRBK2)

Chez www.anticorps-enligne.fr sont 118 Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) Anticorps de 22 de différents fournisseurs disponibles. De plus, nous expédions ADRBK2 Protéines (9) et ADRBK2 Kits (4) et beaucoup plus de produits pour cette protéine. Un total de 137 ADRBK2 produits sont actuellement listés.

Synonymes:: 4833444A01Rik, Adrbk-2, AI851927, AW551196, Bark-2, BARK2, Grk3, si:dz221d18.1

afficher tous les anticorps	Gène	GeneID	UniProt
	ADRBK2	320129	Q3UYH7
	ADRBK2	157	P35626
	ADRBK2	25372	P26819
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Human Polyclonal ADRBK2 Primary Antibody pour WB - ABIN390986 : Rao, Rapoport, Kim: Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients. dans The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2009 (PubMed)
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Human Polyclonal ADRBK2 Primary Antibody pour EIA, IHC (p) - ABIN950649 : Gratacòs, Costas, de Cid, Bayés, González, Baca-García, de Diego, Fernández-Aranda, Fernández-Piqueras, Guitart, Martín-Santos, Martorell, Menchón, Roca, Sáiz-Ruiz, Sanjuán, Torrens, Urretavizcaya et al.: Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and ... dans American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009 (PubMed)
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Plus d’anticorps contre ADRBK2 partenaires d’interaction

Mouse (Murine) Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) interaction partners

GRK3 controls cardiac alpha1-adrenergic receptor responsiveness

Human Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) interaction partners

Study found that GRK3 was significantly overexpressed in 162 pairs of colon cancer tissues than in the matched noncancerous mucosa. These data show that aberrant expression of GRK3 plays an important role in promoting colon cancer progression through enhanced proliferation and reduced apoptosis.
hat (Montrer MGEA5 Anticorps) expression of GRK3 was down-regulated in pancreatic ductal adenocarcinoma and was an independent prognostic factor
GRK3 is a new critical activator of neuroendocrine phenotypes and mediator of CREB (Montrer CREB1 Anticorps) activation in promoting neuroendocrine differentiation of prostate cancer cells.
effects of GRK3 modulation appear to be specific to chemokine (Montrer CCL1 Anticorps)-mediated migration behaviors without influencing tumor cell proliferation or survival
data are consistent with the possibility that oncogenes can induce cellular stiffness via an HDAC6 (Montrer HDAC6 Anticorps)-induced reorganization of the vimentin (Montrer VIM Anticorps) intermediate filament network
Data indicate that CXCL12 (Montrer CXCL12 Anticorps)-induced phosphorylation at CXCR4 (Montrer CXCR4 Anticorps) S346/347 was mediated by GRK2/3.
In oral squamous cell carcinomas, malignant cells and surrounding tissue overexpress the ADRBK2 gene.
A reduced cortical concentration of GRK3 in schizophrenia (resembling that in aging) may result in altered G protein-dependent signaling, thus contributing to prefrontal deficits in schizophrenia.
GRK3 is a negative regulator of cell growth whose expression is preferentially reduced in glioblastoma of the classical subtype as a consequence of activity in primary gliomagenic pathways.
mRNA levels for GRK3 were inversely correlated with systolic and diastolic blood pressure (day, night and 24 h), which suggests a protective role for GRK3 in the regulation of human blood pressure

Zebrafish Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) interaction partners

beta-arrestin 2 (Montrer ARRB2 Anticorps) and GRK2 (Montrer ADRBK1 Anticorps) colocalize with S1p2 (Montrer S1PR2 Anticorps) in developing zebrafish embryos and depletion of GRK2 (Montrer ADRBK1 Anticorps) in the S1p2 (Montrer S1PR2 Anticorps) R150H miles apart zebrafish partially rescued cardia bifida.
GRK2 (Montrer ADRBK1 Anticorps) and GRK5 (Montrer GRK5 Anticorps) control cardiac function as well as morphogenesis during development although with different morphological outcomes.
Data suggest that a G protein-coupled receptor (Montrer GPBAR1 Anticorps) kinase, perhaps GRK2 (Montrer ADRBK1 Anticorps) or 3, functions as a vertebrate kinase for Smoothened (Montrer SMO Anticorps), promoting Hedgehog (Montrer SHH Anticorps) signal transduction during early development.
These data thus reveal a novel kinase activity-independent function for GRK and establish a role for GRK2 as a cell-cycle regulator during early embryonic development.

Cow (Bovine) Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) interaction partners

Fusion proteins containing the c-terminus of GPCR kinase 3 (GRK3ct) and either the fluorescent protein cerulean or Renilla luciferase bind to venus-labeled Gbetagamma dimers, resulting in Forster or bioluminescence resonance energy transfer.

ADRBK2 profil antigène

Antigen Summary

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

Alternative names and synonyms associated with ADRBK2

G protein-coupled receptor kinase 3 (GRK3) anticorps
G protein-coupled receptor kinase 3 (grk3) anticorps
G protein-coupled receptor kinase 3 (Grk3) anticorps

4833444A01Rik anticorps
Adrbk-2 anticorps
AI851927 anticorps
AW551196 anticorps
Bark-2 anticorps
BARK2 anticorps
Grk3 anticorps
si:dz221d18.1 anticorps

Protein level used designations for ADRBK2

adrenergic, beta, receptor kinase 2 , beta-adrenergic receptor kinase 2-like , beta ARK2 , beta-ARK-2 , beta-adrenergic receptor kinase 2 , G-protein-coupled receptor kinase 3 , adrenergic receptor kinase, beta 2 (G-protein-linked receptor kinase) , G-protein coupled receptor kinase 2/3 , GRK2/3

GENE ID	SPECIES
486327	Canis lupus familiaris
100065495	Equus caballus
100379889	Xenopus (Silurana) tropicalis
100396838	Callithrix jacchus
714510	Macaca mulatta
100156449	Sus scrofa
100614029	Pan troglodytes
320129	Mus musculus
157	Homo sapiens
25372	Rattus norvegicus
569403	Danio rerio
416904	Gallus gallus
282136	Bos taurus

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