anti-Humain MSH2 anticorps pour ELISA

Recommended MSH2 Antibody

Antigène
MSH2 Anticorps
  • COCA1
  • FCC1
  • HNPCC
  • HNPCC1
  • LCFS2
  • AI788990
  • wu:fc06b02
  • wu:fc13e09
  • zgc:55333
  • msh2
  • mutS homolog 2
  • mutS homolog 2 (E. coli)
  • mutS homolog 2 L homeolog
  • MutS protein homolog 2
  • MSH2
  • Msh2
  • msh2
  • msh2.L
Reactivité
Humain, Singe
170
66
43
9
7
6
5
4
3
3
3
2
1
1
1
1
1
Hôte
Souris
112
56
3
Clonalité
Monoclonal
Conjugué
Inconjugué
5
4
4
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
123
62
56
45
34
25
19
14
13
9
7
3
2
1
Options

Images

N° du produit ABIN1724643
$ 345.40
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
22.592318 ABIN932932 IF IHC ELISA WB Mouse IgG1 1B3=3A2B8C 0
17.047895 ABIN518023 PLA ELISA WB Mouse IgG2a kappa AA 835-934 4B2 0
16 ABIN1844441 ELISA IF/ICC IHC WB Mouse IgG1 0
16 ABIN3031883 FACS IF ELISA WB Rabbit Ig Fraction AA 637-665 Polyclonal 0
14.047895 ABIN518022 ELISA WB Mouse IgG2a kappa AA 835-934 2G9 0
13.592318 ABIN4901963 ELISA WB Mouse IgG2b 4G5-E11-D9 0
13.592318 ABIN3185692 ELISA IF IHC Rabbit IgG Internal Region Polyclonal 0
13.592318 ABIN4901962 ELISA IF IHC (p) WB Mouse IgG1 1B3=3A2B8C 0
13.592318 ABIN2146966 IF IHC ELISA WB Rabbit IgG Polyclonal 0
13.592318 ABIN2146967 IF IHC ELISA Rabbit IgG Polyclonal 0
13.592318 ABIN966594 IHC ELISA WB IgG1 2
10 ABIN2869168 ELISA ICC IHC WB Mouse IgG1 1B3-3A2B8C 0
10 ABIN6263384 ELISA ICC IF IHC WB Rabbit IgG Polyclonal 0
10 ABIN5583815 ELISA IF IHC (p) WB Mouse IgG1 1B3 (3A2B8C) 0
7 ABIN1534471 IF IHC ELISA Rabbit IgG AA 541-590 Polyclonal 1
7 ABIN2890014 ELISA IF IHC IHC (p) Rabbit IgG AA 541-590 Polyclonal 0
7 ABIN518025 ELISA WB Mouse IgG2a kappa AA 835-934 4F11 0
7 ABIN518024 ELISA WB Mouse IgG2a kappa AA 835-934 3E7 0
7 ABIN2464085 IHC ELISA WB Mouse IgG1 3A2B8C 0
7 ABIN561853 ELISA WB Mouse AA 835-934 Polyclonal 0

General

Antigène MSH2 Anticorps
Reactivité Humain, Singe
(170), (66), (43), (9), (7), (6), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Hôte Souris
(112), (56), (3)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Inconjugué
(5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(123), (62), (56), (45), (34), (25), (19), (14), (13), (9), (7), (3), (2), (1)
Pubmed 2 références disponible
Fournisseur

Détail du produit

Détail du antigène Information d'application Stockage Référence Images
Immunogène Purified recombinant fragment of human MSH2 expressed in E. Coli.
Clone 1B3
Isotype IgG1

Détail du antigène

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Antigène
Sujet MSH2 is a 100 kDa nuclear antigen and encodes a protein of 934 amino acids. The MSH2 gene is one of 4 known genes encoding proteins involved in the repair of mismatch nucleotides following DNA replication or repair. Mutations in the MSH2 gene contribute to the development of sporadic colorectal carcinoma. MSHS mutations are responsible for 50 % of inherited non-polyposis colorectal (HNPCC). The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process.
Poids moléculaire 105 kDa
ID gène 4436
HGNC 4436
Pathways Réparation de l'ADN, Production of Molecular Mediator of Immune Response

Information d'application

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Indications d'application ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
Restrictions For Research Use only

Stockage

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Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C,-20 °C
Stockage commentaire 4°C, -20°C for long term storage

Référence

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Background publications

Palombo, Hughes, Jiricny, Truong, Hsuan: "Mismatch repair and cancer." dans: Nature, Vol. 367, Issue 6462, pp. 417, 1994

Papadopoulos, Nicolaides, Wei, Ruben, Carter, Rosen, Haseltine, Fleischmann, Fraser, Adams: "Mutation of a mutL homolog in hereditary colon cancer." dans: Science (New York, N.Y.), Vol. 263, Issue 5153, pp. 1625-9, 1994

Images

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Images (Fournisseur)
Immunocytochemistry (ICC) image for anti-MSH2 antibody (ABIN1724643) anti-MSH2 antibody
Immunohistochemistry (IHC) image for anti-MSH2 antibody (ABIN1724643) anti-MSH2 antibody (Image 2)
Western Blotting (WB) image for anti-MSH2 antibody (ABIN1724643) anti-MSH2 antibody (Image 3)