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RUNX1 Produits

(Runt-Related Transcription Factor 1 (RUNX1))
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories RUNX1 en vedette

RUNX1 Anticorps

High quality antibodies with extensive validation data.

RUNX1 Kits ELISA

Reliable ELISA kits for a wide range of species.

RUNX1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RUNX1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (2)
  • (5)
N° du produit ABIN514054
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (9)
N° du produit ABIN6147309
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN3022804
Quantité 100 μL
Fiche technique Fiche technique

RUNX1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648548
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648547
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380825
Quantité 2 x 96 tests
Fiche technique Fiche technique

RUNX1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (2)
N° du produit ABIN2731253
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124936
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318992
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits RUNX1

Hong, He, Li, Chu, Pu, Tong, Joshi, Tang, Li: "Runt-related transcription factor 1 promotes apoptosis and inhibits neuroblastoma progression in vitro and in vivo." dans: Journal of experimental & clinical cancer research : CR, Vol. 39, Issue 1, pp. 52, (2020) (PubMed).

Illendula, Gilmour, Grembecka, Tirumala, Boulton, Kuntimaddi, Schmidt, Wang, Pulikkan, Zong, Parlak, Kuscu, Pickin, Zhou, Gao, Mishra, Adli, Castilla, Rajewski, Janes, Guzman, Bonifer, Bushweller: "Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers." dans: EBioMedicine, Vol. 8, pp. 117-31, (2016) (PubMed).

Miao, Zhao, Zhao, Wang, Liu, Ma, Xue: "MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5." dans: Cellular signalling, Vol. 27, Issue 1, pp. 156-67, (2015) (PubMed).

Dobson, Taipaleenmäki, Hu, Hong, van Wijnen, Stein, Stein, Lian, Pratap: "hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3." dans: Cancer cell international, Vol. 14, pp. 73, (2014) (PubMed).

Ferrari, Mohammed, Nixon, Mason, Mallon, McMillan, Morris, Cameron, Edwards, Blyth: "Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer." dans: PLoS ONE, Vol. 9, Issue 6, pp. e100759, (2014) (PubMed).

Mochin, Underwood, Cooper, McLenithan, Pierce, Nalvarte, Arbiser, Karlsson, Moise, Moskovitz, Passaniti: "Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells." dans: Microvascular research, Vol. 97, pp. 55-64, (2014) (PubMed).

Du, Li, Zhong, Fan, Qiao, He, Fu, Wang, Ye: "Brain death induces the alteration of liver protein expression profiles in rabbits." dans: International journal of molecular medicine, Vol. 34, Issue 2, pp. 578-84, (2014) (PubMed).

Keita, Bachvarova, Morin, Plante, Gregoire, Renaud, Sebastianelli, Trinh, Bachvarov: "The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion." dans: Cell cycle (Georgetown, Tex.), Vol. 12, Issue 6, pp. 972-86, (2013) (PubMed).

Niu, Kondo, Nakazawa, Oishi, Kawasaki, Mochizuki, Yamane, Katoh: "Transcription factor Runx2 is a regulator of epithelial-mesenchymal transition and invasion in thyroid carcinomas." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 92, Issue 8, pp. 1181-90, (2012) (PubMed).

Taniuchi, Osato, Ito: "Runx1: no longer just for leukemia." dans: The EMBO journal, Vol. 31, Issue 21, pp. 4098-9, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à RUNX1

uncharacterized LOC473981 (LOC473981), runt-related transcription factor (runt), runt related transcription factor 1 (Runx1), runt related transcription factor 1 (RUNX1), runt-related transcription factor 1 (runx1), runt related transcription factor 1 L homeolog (runx1.L), runt-related transcription factor 1 (RUNX1), runt-related transcription factor 1 (Runx1), AI462102, aml, aml-1, AML1, aml1, Aml1, AML1-EVI-1, aml1-evi-1, AMLCR1, amlcr1, Cbfa2, CBFA2, cbfa2, EVI-1, evi-1, Pebp2a2, PEBP2aB, pebp2ab, Pebpa2b, Runx-1, RUNX1, runx1, runxa, XAML, Xaml1

Protein level used designations for RUNX1

  • runt-related transcription factor 1
  • runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)
  • runt-related transcription factor
  • runt protein
  • CBF-alpha-2
  • PEA2-alpha B
  • PEBP2-alpha B
  • SL3-3 enhancer factor 1 alpha B subunit
  • SL3/AKV core-binding factor alpha B subunit
  • acute myeloid leukemia 1 protein
  • core binding factor alpha 2
  • core-binding factor subunit alpha-2
  • oncogene AML-1
  • polyomavirus enhancer-binding protein 2 alpha B subunit
  • runt domain, alpha subunit 2
  • AML1-EVI-1 fusion protein
  • core-binding factor, runt domain, alpha subunit 2
  • aml1
  • runt-related transcription factor a
  • runx1a
  • Acute myeloid leukemia 1 protein
  • Core-binding factor subunit alpha-2
  • aml1 oncogene
  • ch-runtB2
  • acute myeloid leukemia 1
  • factor, runt domain, alpha subunit 2
  • core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene)
  • runt related transcription factor 1
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