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RUNX1T1 Produits

(Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Catégories

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010].

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Catégories RUNX1T1 en vedette

RUNX1T1 Anticorps

High quality antibodies with extensive validation data.

RUNX1T1 Kits ELISA

Reliable ELISA kits for a wide range of species.

RUNX1T1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RUNX1T1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
N° du produit ABIN560190
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, ChIP, ChIP-seq
Validations
  • (3)
N° du produit ABIN5775090
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
N° du produit ABIN7165188
Quantité 100 μg
Fiche technique Fiche technique

RUNX1T1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969697
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1150734
Quantité 96 tests
Fiche technique Fiche technique

RUNX1T1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318994
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318996
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093943
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RUNX1T1

Chu, Liu, Nix, Wu, Ralston, Yates, Meyer: "Sperm chromatin proteomics identifies evolutionarily conserved fertility factors." dans: Nature, Vol. 443, Issue 7107, pp. 101-5, (2006) (PubMed).

Abdelhaleem: "RNA helicases: regulators of differentiation." dans: Clinical biochemistry, Vol. 38, Issue 6, pp. 499-503, (2005) (PubMed).

Hoet, Cohen, Kent, Rookey, Schoonbroodt, Hogan, Rem, Frans, Daukandt, Pieters, van Hegelsom, Neer, Nastri, Rondon, Leeds, Hufton, Huang, Kashin, Devlin, Kuang, Steukers, Viswanathan, Nixon, Sexton et al.: "Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity. ..." dans: Nature biotechnology, Vol. 23, Issue 3, pp. 344-8, (2005) (PubMed).

Martinez, Drescher, Riehle, Cullmann, Vornlocher, Ganser, Heil, Nordheim, Krauter, Heidenreich: "The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells." dans: BMC cancer, Vol. 4, pp. 44, (2004) (PubMed).

Zeeman, Stoop, Boter, Gillis, Castrillon, Oosterhuis, Looijenga: "VASA is a specific marker for both normal and malignant human germ cells." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 82, Issue 2, pp. 159-66, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (runx1t1), RUNX1 translocation partner 1 L homeolog (runx1t1.L), RUNX1 translocation partner 1 (RUNX1T1), runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (Runx1t1), RUNX1 translocation partner 1 (Runx1t1), AML1T1, CBFA2T1, Cbfa2t1, Cbfa2t1h, CDR, ETO, MTG8, si:ch211-232j17.1, wu:fi14b07, zgc:154044, ZMYND2

Protein level used designations for RUNX1T1

  • protein CBFA2T1
  • MTG8
  • MTG8/ETOb
  • expressed during postmitotic spinal neurons, most likely in motorneurons
  • acute myelogenous leukemia 1 translocation 1, cyclin-D related
  • core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related
  • eight twenty one protein
  • myeloid translocation gene on 8q22
  • zinc finger MYND domain-containing protein 2
  • CBFA2T1 identified gene homolog
  • acute myelogenous leukemia 1 translocation 1 protein
  • core-binding factor, runt domain, alpha subunit 2
  • cyclin D-related
  • translocated to, 1
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