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RUNX3 Produits

(Runt-Related Transcription Factor 3 (RUNX3))

Catégories

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories RUNX3 en vedette

RUNX3 Anticorps

High quality antibodies with extensive validation data.

RUNX3 Kits ELISA

Reliable ELISA kits for a wide range of species.

RUNX3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RUNX3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF (p), FACS, IF (cc), IHC (p), ICC, IHC (fro)
Validations
  • (1)
  • (1)
N° du produit ABIN1714069
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (7)
N° du produit ABIN5611280
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (1)
  • (5)
N° du produit ABIN514065
Quantité 50 μg
Fiche technique Fiche technique

RUNX3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959208
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648562
Quantité 96 tests
Fiche technique Fiche technique

RUNX3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124938
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1319002
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3123245
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RUNX3

Li, Zhao, Huang, Wang, Zhu, Cao, Xiong, Deng: "MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway." dans: Gene, Vol. 641, pp. 240-247, (2017) (PubMed).

Zhu, Xu, Hu, Feng, Jiang, Hou, Cao, Han, Ling, Ge: "Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma." dans: Journal of experimental & clinical cancer research : CR, Vol. 33, Issue 1, pp. 114, (2015) (PubMed).

Shi, Wang, Liu, Chen: "Inactivation of RUNX3 predicts poor prognosis in esophageal squamous cell carcinoma after Ivor-Lewis esophagectomy." dans: Medical oncology (Northwood, London, England), Vol. 31, Issue 12, pp. 309, (2014) (PubMed).

Yoshikawa, Murakami, Senzaki, Masuda, Ozaki, Ito, Shiga: "Coexpression of Runx1 and Runx3 in mechanoreceptive dorsal root ganglion neurons." dans: Developmental neurobiology, Vol. 73, Issue 6, pp. 469-79, (2013) (PubMed).

Chuang, Ito, Ito: "RUNX family: Regulation and diversification of roles through interacting proteins." dans: International journal of cancer. Journal international du cancer, Vol. 132, Issue 6, pp. 1260-71, (2013) (PubMed).

Lotem, Levanon, Negreanu, Leshkowitz, Friedlander, Groner: "Runx3-mediated transcriptional program in cytotoxic lymphocytes." dans: PLoS ONE, Vol. 8, Issue 11, pp. e80467, (2013) (PubMed).

Reis, Rogoz, Costa-Pinto, Taniuchi, Mucida: "Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity." dans: Nature immunology, Vol. 14, Issue 3, pp. 271-80, (2013) (PubMed).

Chopin, Seillet, Chevrier, Wu, Wang, Morse, Belz, Nutt: "Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks." dans: The Journal of experimental medicine, Vol. 210, Issue 13, pp. 2967-80, (2013) (PubMed).

Zou, Li, Klein, Xiang: "Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord." dans: Developmental biology, Vol. 364, Issue 2, pp. 114-27, (2012) (PubMed).

Presnell, Zhang, Chlebowy, Al-Attar, Lutz: "Differential transcription factor use by the KIR2DL4 promoter under constitutive and IL-2/15-treated conditions." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4394-404, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à RUNX3

runt-related transcription factor 3 (runx3), runt-related transcription factor 3 (RUNX3), runt related transcription factor 3 (RUNX3), runt related transcription factor 3 (runx3), runt related transcription factor 3 L homeolog (runx3.L), runt related transcription factor 3 (Runx3), runt-related transcription factor 3 (Runx3), aml2, AML2, CBFA3, cbfa3, Cbfa3, frrunx3, Pebp2a3, pebp2ac, PEBP2aC, RUNX3, runx3, runxb

Protein level used designations for RUNX3

  • runt-related transcription factor b
  • runt-related transcription factor 3
  • core-binding factor 3
  • frRunx3/p45
  • CBF-alpha-3
  • PEA2-alpha C
  • PEBP2-alpha C
  • SL3-3 enhancer factor 1 alpha C subunit
  • SL3/AKV core-binding factor alpha C subunit
  • acute myeloid leukemia 2 protein
  • core binding factor alpha 3
  • core-binding factor subunit alpha-3
  • oncogene AML-2
  • polyomavirus enhancer-binding protein 2 alpha C subunit
  • runt domain, alpha subunit 3
  • transcription factor AML2/CBFA3
  • PEA2 alpha C
  • PEBP2 alpha C
  • acute myeloid leukemia gene 2
  • core-binding factor, runt domain, alpha subunit 3
  • transcription factor AML2
  • Runt related transcription factor 3
  • Runx3 MASN-variant
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