RUNX2 Produits
(Runt-Related Transcription Factor 2 (RUNX2))
Catégories
This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008].
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Catégories RUNX2 en vedette
RUNX2 Anticorps
High quality antibodies with extensive validation data.
RUNX2 Kits ELISA
Reliable ELISA kits for a wide range of species.
RUNX2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RUNX2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (2)
- (9)
N° du produit
ABIN560185
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
- (7)
N° du produit
ABIN514045
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
- (12)
N° du produit
ABIN3016834
Quantité
100 μL
Fiche technique
Fiche technique
RUNX2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6959206
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
N° du produit
ABIN6959207
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969977
Quantité
96 tests
Fiche technique
Fiche technique
RUNX2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124937
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1318998
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319000
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RUNX2
: "The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast." dans: Journal of orthopaedic surgery and research, Vol. 15, Issue 1, pp. 327, (2021) (PubMed).: "Human proximal tubular cells can form calcium phosphate deposits in osteogenic culture: role of cell death and osteoblast-like transdifferentiation." dans: Cell death discovery, Vol. 5, pp. 57, (2019) (PubMed).
: "Growth Plate Borderline Chondrocytes Behave as Transient Mesenchymal Precursor Cells." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, (2019) (PubMed).
: "Role of RUNX2 transcription factor in epithelial mesenchymal transition in non-small cell lung cancer lung cancer: Epigenetic control of the RUNX2 P1 promoter." dans: Tumour biology, Vol. 41, Issue 5, pp. 1010428319851014, (2019) (PubMed).
: "Silent Mating Type Information Regulation 2 Homolog (SIRT1) Influences Osteogenic Proliferation and Differentiation of MC3T3-E1 Cells via Regulation of miR-132-3p." dans: Medical science monitor : international medical journal of experimental and clinical research, Vol. 25, pp. 2289-2295, (2019) (PubMed).
: "Rotator Cuff Tenocytes Differentiate into Hypertrophic Chondrocyte-Like Cells to Produce Calcium Deposits in an Alkaline Phosphatase-Dependent Manner." dans: Journal of clinical medicine, Vol. 8, Issue 10, (2019) (PubMed).
: "Docosahexaenoic Acid (DHA) Inhibits Bone Morphogenetic Protein-2 (BMP-2) Elevated Osteoblast Potential of Metastatic Breast Cancer (MDA-MB-231) Cells in Mammary Microcalcification." dans: Nutrition and cancer, pp. 1-11, (2019) (PubMed).
: "Rapid fabrication of vascularized and innervated cell-laden bone models with biomimetic intrafibrillar collagen mineralization." dans: Nature communications, Vol. 10, Issue 1, pp. 3520, (2019) (PubMed).
: "Icaritin induces MC3T3-E1 subclone14 cell differentiation through estrogen receptor-mediated ERK1/2 and p38 signaling activation." dans: Biomedicine & pharmacotherapy, Vol. 94, pp. 1-9, (2018) (PubMed).
: "mTORC1 activation downregulates FGFR3 and PTH/PTHrP receptor in articular chondrocytes to initiate osteoarthritis." dans: Osteoarthritis and cartilage, Vol. 25, Issue 6, pp. 952-963, (2018) (PubMed).
Synonymes et noms alternatifs relatifs à RUNX2
runt related transcription factor 2 (RUNX2), runt-related transcription factor 2a (runx2a), runt related transcription factor 2 (Runx2), runt-related transcription factor 2 (Runx2), runt related transcription factor 2 (runx2), runt-related transcription factor 2 (LOC703331), runt-related transcription factor 2 (LOC100549663), runt related transcription factor 2 L homeolog (runx2.L), runt-related transcription factor 2 (RUNX2), AML3, aml3, Cbf, CBF-alpha-1, Cbfa-1, CBFA1, Cbfa1, cbfa1, CCD, ccd, CCD1, ccd1, CLCD, LS3, OSF-2, OSF2, Osf2, osf2, PEA2aA, pea2aa, Pebp2a1, pebp2a1, pebp2a2, PEBP2aA, pebp2aa, pebp2aa1, Pebpa2a, runx2, RUNX2Protein level used designations for RUNX2
- PEA2-alpha A
- PEBP2-alpha A
- SL3-3 enhancer factor 1 alpha A subunit
- SL3/AKV core-binding factor alpha A subunit
- acute myeloid leukemia 3 protein
- core-binding factor, runt domain, alpha subunit 1
- oncogene AML-3
- osteoblast-specific transcription factor 2
- polyomavirus enhancer-binding protein 2 alpha A subunit
- runt-related transcription factor 2
- transcription factor Runx2a
- AKV core binding factor
- CBF-alpha-1
- PEBP2 alpha A
- core binding factor alpha 1
- runt domain, alpha subunit 1
- core-binding factor subunit alpha-1
- runt related transcription factor 2
- transcription factor Cbfa1
- runt-related factor 2
- core binding factor alpha 1 subunit
- runt-related transcription factor 2-like
- Runx2 spliced isoform
- runt-related transcription factor 2 type I
- runt-related transcription factor 2 type II
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