SCN5A Produits
(Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
Catégories
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories SCN5A en vedette
SCN5A Anticorps
High quality antibodies with extensive validation data.
SCN5A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SCN5A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (6)
N° du produit
ABIN185467
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (4)
N° du produit
ABIN2776088
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (2)
N° du produit
ABIN7182719
Quantité
100 μL
Fiche technique
Fiche technique
SCN5A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6220157
Quantité
96 tests
Fiche technique
Fiche technique
SCN5A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319281
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3076758
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3130186
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SCN5A
: "Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami." dans: Scientific reports, Vol. 6, pp. 29538, (2016) (PubMed).: "Nicorandil improves electrical remodelling, leading to the prevention of electrically induced ventricular tachyarrhythmia in a mouse model of desmin-related cardiomyopathy." dans: Clinical and experimental pharmacology & physiology, Vol. 41, Issue 1, pp. 89-97, (2013) (PubMed).
: "Similar arrhythmicity in hypertrophic and fibrotic cardiac cultures caused by distinct substrate-specific mechanisms." dans: Cardiovascular research, Vol. 97, Issue 1, pp. 171-81, (2012) (PubMed).
: "Optical mapping of cryoinjured rat myocardium grafted with mesenchymal stem cells." dans: American journal of physiology. Heart and circulatory physiology, Vol. 302, Issue 1, pp. H270-7, (2011) (PubMed).
: "The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice." dans: Cardiovascular research, Vol. 87, Issue 1, pp. 73-82, (2010) (PubMed).
: "Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion." dans: Cancer research, Vol. 70, Issue 17, pp. 6957-67, (2010) (PubMed).
: "Sodium channel mutations and susceptibility to heart failure and atrial fibrillation." dans: JAMA, Vol. 293, Issue 4, pp. 447-54, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à SCN5A
sodium voltage-gated channel alpha subunit 5 (SCN5A), sodium channel, voltage-gated, type V, alpha (Scn5a), sodium voltage-gated channel alpha subunit 5 (Scn5a), CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, mH1, Nav1.5, Nav1.5c, PFHB1, SCAL, SkM1, SkM2, SSS1, VF1Protein level used designations for SCN5A
- sodium channel, voltage-gated, type V, alpha subunit
- voltage-gated sodium channel type V alpha
- sodium channel protein type 5 subunit alpha
- voltage-gated sodium channel cardiac isoform Nav1.5
- sodium channel protein cardiac muscle subunit alpha
- sodium channel protein type V subunit alpha
- sodium channel voltage-gated type V alpha polypeptide
- sodium channel, voltage-gated, type V, alpha polypeptide
- voltage-gated sodium channel subunit alpha Nav1.5
- cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit
- cardiac sodium channel
- sodium channel alpha subunit
- sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)
- voltage-gated sodium channel alpha subunit
- sodium channel, voltage-gated, type V, alpha polypeptide (long (electrocardiographic) QT syndrome 3)
- sodium channel, voltage-gated, type 5, alpha subunit
- voltage-gated sodium channel Nav1.5c
- oltage-gated sodium channel type V alpha
- voltage-dependent sodium channel SCN10A
- voltage-gated sodium channel H
- voltage-gated sodium channel type V alpha polypeptide
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